Table 1.

Clinical questions and Patient/population, Intervention, Comparison and Outcome (PICO) statements.

Question	Population	Intervention	Comparison	Outcomes
1. What are the indications for routine and sleep EEG?	Patient in EEG	EEG recording	No EEG recording	Impact on diagnostics, management decisions or prognostication
2. What are the minimum technical standards for routine and sleep EEG?	Not practically applicable
3. What provocation methods should be used in routine and sleep EEG and how?	Patient in EEG	Photic stimulation Hyperventilation Other provocation	No provocation	Epileptiform abnormality Seizure -epileptic -non-epileptic Adverse effects
4. What should be a minimum duration of routine and sleep EEG to be optimally diagnostic?	Patient in EEG	EEG duration 1	EEG duration 2	Abnormal EEG finding
5. Should sleep deprivation (partial or all night/24h) used to obtain sleep?	Patient in EEG	Sleep deprivation	Natural sleep	Sleep Adverse effects Cost-benefit
6. Can melatonin or other drugs be used for sleep induction?	Patient in EEG	Melatonin Other sleep-inducing drug	Sleep deprivation Sleep inducing drug	Sleep Adverse effects Cost-benefit

EEG, electroencephalography