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. Author manuscript; available in PMC: 2024 Mar 1.
Published in final edited form as: J Control Release. 2023 Feb 6;355:149–159. doi: 10.1016/j.jconrel.2023.01.065

Table 1.

Properties of Pro-NP™s used for Ktrans imaging and antioxidant therapy.

Particle Size (nm) PDI Resus-pended size (nm) Resus-pended PDI Zeta potential (mV) Initial burst enzyme activity (U/mg Pro-NP™) Sustained release enzyme activity (U/mg Pro-NP™) Gd concentration (mmol/mg Pro-NP™)
Gd-Pro-NP™ 214 0.036 292 0.131 −10.3 ~ ~ 7.56×10−6
SOD1-Pro-NP™ 203 0.12 274 0.132 −15.3 658 43 ~
CAT-Pro-NP™ 218 0.103 284 0.117 −25.7 298 37 ~