Table 1.
Baseline characteristics of participants without and with interstitial fibrosis [ECV quartile 1 (q1) vs. ECV quartile 4 (q4)].
| ECVq1 (N = 156) | ECVq4 (N = 156) | p-value | |
|---|---|---|---|
| Age (years) | 58 (8) | 58 (9) | >0.90 |
| Gender | 0.14 | ||
| Female | 96 (62%) | 83 (53%) | |
| Male | 60 (38%) | 73 (47%) | |
| Race | 0.80 | ||
| White | 76 (49%) | 74 (47%) | |
| Chinese American | 17 (11%) | 21 (13%) | |
| Black | 38 (24%) | 40 (26%) | |
| Hispanic | 25 (16%) | 21 (13%) | |
| BMI (kg/m2) | 29.6 (5.6) | 27.3 (5.5) | <0.001 |
| Systolic BP (mmHg) | 124 (21) | 118 (19) | 0.022 |
| Diastolic BP (mmHg) | 68 (9) | 67 (10) | 0.70 |
| Use of anti-hypertension Medication | 77 (49%) | 71 (46%) | 0.50 |
| Total Cholesterol (mg/dl) | 179 (33) | 181 (37) | 0.70 |
| HDL Cholesterol (mg/dl) | 53 (14) | 57 (18) | 0.032 |
| Use of lipid lowering medication | 72 (46%) | 53 (34%) | 0.028 |
| Cigarette smoking status | <0.001 | ||
| Never | 76 (49%) | 50 (32%) | |
| Former | 78 (50%) | 86 (55%) | |
| Current | 2 (1%) | 20 (13%) | |
| Diabetes | 0.03 | ||
| Normal | 89 (57%) | 112 (72%) | |
| Impaired fasting glucose | 35 (22%) | 20 (13%) | |
| Diabetes | 32 (21%) | 24 (16%) | |
| eGFR (mL/min/1.73 m2) | 85 (14) | 86 (15) | 0.60 |
| ECV (%) | 23.5 (1.0) | 30.3 (1.5) | <0.001 |
| Gross family income | 0.11 | ||
| $0–$19,999 | 22 (15%) | 20 (13%) | |
| $20,000–$49,999 | 63 (42%) | 48 (31%) | |
| $50,000 or more | 66 (44%) | 85 (56%) |
Figures are numbers (%) and mean (standard deviation). BMI, body mass index; BP, blood pressure; HDL, high-density lipoprotein; eGFR, estimated glomerular filtration rate; ECV, extracellular volume.