Table 2.
Mortality rate and changes in body weight, heart weight, and heart weight/body weight after 12 days of treatment.
| Ctrl | DOX | DOX + Api | DOX + Api-AuNPs | |
|---|---|---|---|---|
| Mortality | 0 | 2 | 1 | 0 |
| BW (g) | 270 ± 5.03 | 203 ± 7.50*** | 218 ± 5.05*** | 254 ± 6.02###$$$ |
| HW (mg) | 1.12 ± 0.08 | 0.62 ± 0.07*** | 0.6 ± 0.08*** | 0.97 ± 0.06##$$ |
| HW/BW (mg/g) | 4.64 ± 0.41 | 3.05 ± 0.67 | 2.75 ± 0.46 | 3.81 ± 0.64 |
Data are presented as Mean ± SEM. BW; body weight (g), HW; heart weight (g), HW/BW; heart weight to body weight (mg/g), Ctrl; Control, DOX; Doxorubicin, Api; Apigenin and Api-AuNPs; Apigenin coated gold nanoparticles.
**P < 0.01 and ***P < 0.001 vs. Ctrl group, ##P < 0.001 and ###P < 0.001 vs. DOX group and $$ P < 0.01 and $$$ P < 0.001 vs. Api + DOX.