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. Author manuscript; available in PMC: 2023 Mar 11.
Published in final edited form as: Nat Rev Neurol. 2011 Apr 12;7(5):263–272. doi: 10.1038/nrneurol.2011.43

Table 1 |.

Clinical heterogeneity of pathologically confirmed CBD

Reference Female:male ratio Age at onset/disease duration (years) Common features at onset (% of patients) Clinical diagnosis* (% of patients)


Limb apraxia Memory impairment Behavioral changes Gait disturbance Speech disorder CBS AD or PD FTD RS

Schneider et al. (1997)18 10:1 67/7.9 64 18 9 9 9 64 27 0 0
Litvan et al. (2000)26 14:13 64/7.0 37 33 33 26 22 22 30 7 4
Murray et al. (2007)16 8:7 61/5.4 33 33 40 27 40 40 13 33 13
Ling et al. (2010)17 9:10 66/6.0 26 37 26 63 16 26 10 5 42
Totals 41:31 65/6.6 38 32 29 33 22 33 21 11 15
*

The total does not equal 100% because some series had final diagnoses other than the diseases listed here. Abbreviations: AD, Alzheimer disease; CBD, corticobasal degeneration; CBS, corticobasal syndrome; FTD, frontotemporal dementia; PD, Parkinson disease; RS, Richardson syndrome.