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. 2023 Mar 2;15(5):1275. doi: 10.3390/polym15051275

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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HOB cell numbers for (a) different concentrations of KGN; (b) PLGA formulations; (c) blended PLGA/PEG-KGN formulations; and (d) blended PLGA/PVP-KGN formulations. KGN-treated wells were exposed to different concentrations of KGN dissolved in DMSO/culture media, with the final concentration of DMSO being 0.1% v/v. DMSO control wells were treated with DMSO/media mixture at the same DMSO concentration. ‘Positive control’ are the wells that were treated with 100% ethanol. Statistical analysis using ANOVA revealed no significant differences between the formulations and negative controls.