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. 2023 Feb 15;12(2):321–339. doi: 10.21037/tcr-22-2036

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2023 Translational Cancer Research. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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The risk scores distribution plots, survival status plots, and heatmaps of four ECM genes in the training and validation cohorts. (A-E, upper panels) Distribution of risk scores based on the ECM-based prognostic signature in the COAD and validation cohorts. (A-E, middle panels) Survival status of CC patients with high- or low-risk scores in the COAD and validation cohorts. (A-E, lower panels) Heatmaps show the expression pattern of four ECM genes that constitute the prognostic signature in the COAD and validation cohorts (lower). ECM, extracellular matrix; TCGA, The Cancer Genome Atlas; COAD, colon adenocarcinoma.