Skip to main content
. Author manuscript; available in PMC: 2023 Mar 11.
Published in final edited form as: Nat Genet. 2020 Jul 20;52(8):790–799. doi: 10.1038/s41588-020-0664-8

Extended Data Fig. 4: GREAT analysis characterizing mCRPC-enriched epigenetic sites.

Extended Data Fig. 4:

(a) GREAT analysis characterizing the gene ontology biological terms most significantly associated with genes proximal to the 17,655 met-ARBS. (b) GREAT analysis characterizing the gene ontology biological terms most significantly associated with genes proximal to the subset 17,655 met-ARBS that are co-occupied by H3K27Ac. Terms associated with genitourinary development are highlighted in yellow. (c) The biological terms most significantly associated with genes proximal to the 2,683 AR sites enriched in primary tumor compared to mCRPC. (d) GREAT analysis of the MSigDB pathway terms most significantly associated with genes proximal to met-ARBS.