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. Author manuscript; available in PMC: 2023 Mar 11.
Published in final edited form as: Nat Genet. 2020 Jul 20;52(8):790–799. doi: 10.1038/s41588-020-0664-8

Table 1 |.

Specimens included in the study by tissue and epigenetic mark

AR FOXA1 HOXB13 H3K27ac H3K4me2 H3K4me3 H3K27me3 ATAC All marks
Total 59 42 42 86 8 10 11 10 268
Normal prostate epithelium 13* 14 14 37+ 4 3 4 4 93
Primary prostate tumor 31* 13 13 32 4 7 7 6 113
mCRPC 15 15 15 17 0 0 0 0 62
Median no. peaks (range) 20,619 (1,577–73,723) 37,691 (3,174 – 99,041) 47,338 (1,709 – 90,075) 34,609 (2,337 – 127,042) 69,558 (41,095 – 83,869) 33,215 (28,952 – 38,447) 254,148 (112,809 – 316,413) 48,139 (25,324 – 60,232)
*

Includes seven normal prostate and 13 primary tumor AR ChIP libraries published previously6.

+

Includes H3K27ac ChIP-seq performed in a specimen derived from human fetal urogenital sinus20.

ChIP-seq experiments performed using PDXs derived from human mCRPC with the exception of two H3K27ac ChIP-seq specimens derived from patient mCRPC liver biopsies.