Table 3. Univariable and multivariable analysis for predictors of cancer-specific survival.
| Characteristics | Univariable | Multivariable | |||
|---|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | ||
| Age >60 years | 1.38 (1.02–1.88) | 0.039 | 1.56 (1.13–2.14) | 0.006* | |
| Sex (male) | 0.94 (0.68–1.30) | 0.717 | – | – | |
| ALI score (low) | 1.81 (1.27–2.60) | 0.001 | 1.46 (1.01–2.10) | 0.043* | |
| T3/4 stage | 9.92 (5.23–18.81) | <0.001 | 5.11 (2.60–10.06) | <0.001* | |
| Lymph node metastasis (presence) | 4.28 (2.83–6.46) | <0.001 | 2.33 (1.50–3.6) | <0.001* | |
| Histological grade (poorly differentiated) | 1.74 (1.13–2.66) | 0.011 | 1.41 (0.91–2.18) | 0.125 | |
| Histological type (signet ring cell or mucinous adenocarcinoma) | 1.16 (0.79–1.70) | 0.459 | – | – | |
| Perineural invasion (presence) | 3.27 (2.38–4.50) | <0.001 | 1.69 (1.20–2.37) | 0.003* | |
| Vessel invasion (presence) | 2.51 (1.85–3.41) | <0.001 | 1.36 (0.99–1.88) | 0.059 | |
*, P value is statistically significant (P<0.05). ALI, advanced lung cancer inflammation index; HR, hazard ratio; CI, confidence interval.