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. 2023 Mar 7;18:1131–1143. doi: 10.2147/IJN.S400798

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© 2023 Zhang et al.

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Effect of ES NPs-HA on neuropathic pain. Experimental timeline of this study (A) Mechanical pain threshold in mice after spinal nerve ligation (B) (n=6/group); Effect of a single treatment of esketamine on mechanical pain in SNL mice (C) (n=8/group); The effect of ES NPs-HA administration on mechanical pain in SNL mice (D) (n=8/group). Data are expressed as the mean ± SEM. *P <0.05; Two-way RM ANOVA followed by the Bonferroni test.