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. 2023 Feb 27;10:rbad014. doi: 10.1093/rb/rbad014

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© The Author(s) 2023. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — Preparation and characterization of ATRA-NPs. (a) Preparation and application of ATRA-NPs for inhibiting cancer growth and metastasis. (b) Experimental factors and levels. (c) Optimization analysis of the response of experimental factors. SEM and TEM images for (d) blank NPs and (e) ATRA-NPs. (f) Particle size, (g) DL and (h) EE of ATRA-NPs prepared under optimized experimental condition (n = 4). (i) Drug release of ATRA-NPs in PBS and PBS containing 5% FBS (n = 3).