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. 2023 Feb 27;10:rbad014. doi: 10.1093/rb/rbad014

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© The Author(s) 2023. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 5. — Effect of Pin1 knockdown on anti-metastatic efficacy of ATRA-NPs. (a) Images and (b) numbers of migrated and invaded HuH7-shV cells after 72 h of treatment (n = 3). (c) Images and (d) numbers of migrated and invaded HuH7-shPin1 cells after 72 h of treatment (n = 3). (e) Images and (f) numbers of migrated and invaded HepG2-shV cells after 72 h of treatment (n = 3). (g) Images and (h) numbers of migrated and invaded HepG2-shPin1 cells after 72 h of treatment (n = 3). (i) Western blot images of PIN1 and EMT marker proteins from HuH7-shV and HuH7-shPin1 cells after 72 h of treatment (n = 3). (j) Western blot images of PIN1 and EMT marker proteins from HepG2-shV and HepG2-shPin1 cells after 72 h of treatment (n = 3).