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. 2023 Mar 7;13(3):e061294. doi: 10.1136/bmjopen-2022-061294

Table 1.

Trial criteria for diagnosis of DCM

MRI indicators Clinical symptoms Neurological signs
Effacement of cerebrospinal fluid (CSF) and deformation of cord Numb hands Pyramidal weakness
T1 signal change Clumsy hands Hyper-reflexia
T2 signal change Bilateral arm paraesthesia Positive Hoffman sign
Segmentation of T2 signal change Gait impairment Upgoing plantar response
Reduction in transverse area of cord Lhermitte’s phenomenon Atrophy of intrinsic hand muscles
Weakness Spasticity/clonus
Broad based, unstable gait

Participants must have at least one MRI indicator, clinical symptom and neurological sign to be eligible for inclusion.

DCM, degenerative cervical myelopathy.