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. 2023 Mar 11;9:38. doi: 10.1038/s41531-023-00476-2

Table 4.

Correlation between CSF inflammatory markers with CSF PD-biomarkers in people with dementia with Lewy bodies.

1-42 t-Tau p181-Tau NFL α-synuclein
Eotaxin-1 n.s. m: 0.321* n = 45 n.s. n.s. n.s.
Factor-VII n.s. f: 0.572* n = 14 f: 0.604* n = 14 n.s. f: 0.552* n = 14
ICAM-1 n.s. n.s. n.s.

t: 0.457*** n = 61

m: 0.649*** n = 41

n.s.
Interleukin-4 f: 0.495* n = 18 n.s. n.s. f: 0.666** n = 17 n.s.
Interleukin-6 n.s. n.s. n.s.

t: 0.341* n = 45

f: 0.656* n = 12

n.s.
Interleukin-8 n.s.

t: 0.407*** n = 66

m: 0.322* n = 45

f: 0.558** n = 21

t: 0.513*** n = 62

m: 0.420** n = 42

f: 0.719*** n = 20

n.s.

t: 0.328** n = 62

f: 0.493* n = 20

Interleukin-18 n.s. n.s. m: 0.359* n = 36 n.s. n.s.
MCP-1 n.s. t: 0.273* n = 66 n.s. n.s. n.s.
MMP3 n.s. f: 0.458* n = 21

t: 0.342** n = 62

m: 0.320* n = 42

t: 0.298* n = 61

m: 0.339* n = 41

t: 0.361** n = 62

f: 0.586** n = 20

MMP9 n.s. n.s. n.s. n.s.

t: 0.302* n = 55

m: 0.328* n = 39

SCF n.s.

t: 0.550*** n = 66

m: 0.380** n = 45

f: 0.801*** n = 21

t: 0.604*** n = 62

m: 0.545*** n = 42

f: 0.772** n = 20

n.s.

t: 0.645*** n = 62

m: 0.573*** n = 42

f: 0.759*** n = 20

VEGF n.s. n.s. n.s.

t: 0.300* n = 61

m: 0.625*** n = 41

n.s.

Pearson correlation: *p < 0.05; **p < 0.01; ***p ≤ 0.001.

t total cohort, m males only, f females only, n.s. not significant.