Table 1.
Glutamine Synthetase+ cell density differences with reduction of FGFR2 signaling.
Control Mean ± SEM cells x 10−5/μm3 | Experimental Mean ± SEM cells x 10−5/μm3 | Difference | p-value | |
---|---|---|---|---|
FGFR2 nKO Medial Frontal Cortex | 0.23 ± 0.01 (n = 3) | 0.47 ± 0.05 (n = 3) | ↑104% | 0.01* |
FGFR2 nKO Hippocampus | 1.20 ± 0.15 (n = 3) | 1.99 ± 0.43 (n = 3) | ↑68% | 0.07¥ |
FGFR2 cKO Hippocampus | 1.55 ± 0.06 (n = 4) | 2.05 ± 0.13 (n = 6) | ↑30% | 0.02* |
FGFR iKO Hippocampus | 1.77 ± 0.19 (n = 3) | 2.09 ± 0.40 (n = 3) | ↑18% | 0.55 |
*p < 0.05, ¥-trending significance, 0.05 ≤ p < 0.10.