FIG. 5.

Predictive amino acid sequence alignment of SWPs from E. intestinalis and E. cuniculi. The predicted amino acid sequences of E. intestinalis (EI) swp1 and swp2 and the E. cuniculi (EC) SWP are compared. Identical amino acids are indicated by reverse shading, while similarities are boxed. Dashes represent gaps introduced to maximize homology. The arrows denote separation of the SWPs into two domains. The hatched box indicates the predicted signal sequence. The asterisks denote 10 conserved cysteine residues. N-glycosylation sites for swp1 (positions 290 to 292) and swp2 (positions 308 to 310) are indicated by stippled boxes. The C-terminal domain of swp2 contains a 12- or 15-amino-acid repeat that is bracketed and numbered. The repeats containing 15 amino acids are double underlined. The predicted amino acid sequence for E. cuniculi was obtained from GenBank (accession number AJ133745).