TABLE 4.
Average survival categorized by surgery type in LUAD patients with specific organ metastases
| Patients | LUAD patients | Without surgery | Average survival (95% CI) | Local tumor destruction | |
|---|---|---|---|---|---|
| N (%) | N (%) | N (%) | Average survival (95% CI) | ||
| With specific organ metastases | 17 529 (43.69%) | 16 958 (96.74%) | 11.71 (11.48–11.94) | 26 (0.15%) | 13.73 (5.09–22.37) |
| With bone metastases | 9440 (26.25%) | 9273 (98.23%) | 10.63 (10.34–10.93) | 12 (0.13%) | 16.58 (4.97–28.19) |
| With brain metastases | 7167 (19.66%) | 6910 (96.41%) | 11.39 (11.04–11.75) | 5 (0.07%) | 2.60 (0.34–4.86) |
| With liver metastases | 3784 (10.60%) | 3734 (98.68%) | 8.24 (7.85–8.62) | 4 (0.11%) | NA |
| With lung metastases | 6661 (17.89%) | 6443 (96.73%) | 12.15 (11.77–12.53) | 12 (0.18%) | 11.25 (2.53–19.97) |
| Metastatic organ no. | |||||
| 1 | 10 507 (26.19%) | 10 043 (95.58%) | 13.14 (12.82–13.47) | 20 (0.19%) | 13.65 (3.08–24.22) |
| 2 | 4899 (12.21%) | 4806 (98.10%) | 10.08 (9.69–10.46) | 5 (0.10%) | NA |
| 3 | 1745 (4.35%) | 1731 (99.20%) | 8.66 (8.08–9.23) | 1 (0.06%) | NA |
| 4 | 378 (0.94%) | 378 (100.00%) | 8.31 (7.20–9.42) | 0 (0.00%) | NA |
| 2–4 | 7022 (17.50%) | 6915 (98.48%) | 9.63 (9.32–9.94) | 6 (0.09%) | NA |
| Patients | Sublobar resection | Lobectomy or extended | ||
|---|---|---|---|---|
| N (%) | Average survival (95% CI) | N (%) | Average survival (95% CI) | |
| With specific organ metastases | 294 (1.68%) | 19.90 (17.46–22.33) | 251 (1.43%) | 35.16 (31.69–38.63) |
| With bone metastases | 104 (1.10%) | 16.36 (12.57–20.14) | 51 (0.54%) | 30.69 (22.11–39.26) |
| With brain metastases | 110 (1.53%) | 18.54 (14.62–22.45) | 142 (1.98%) | 33.89 (29.44–38.35) |
| With liver metastases | 31 (0.82%) | 16.16 (6.90–25.43) | 15 (0.40%) | 32.67 (16.79–48.54) |
| With lung metastases | 139 (2.09%) | 22.47 (18.97–25.98) | 67 (1.01%) | 35.52 (28.86–42.19) |
| Metastatic organ no. | ||||
| 1 | 214 (2.04%) | 20.88 (18.00–23.76) | 230 (2.19%) | 36.58 (32.91–40.24) |
| 2 | 70 (1.43%) | 17.84 (12.69–22.99) | 18 (0.37%) | 22.28 (12.63–31.92) |
| 3 | 10 (0.57%) | 13.3 (4.21–22.39) | 3 (0.17%) | NA |
| 4 | 0 (0.00%) | NA | 0 (0.00%) | NA |
| 2–4 | 80 (1.14%) | 17.28 (12.67–21.88) | 21 (0.30%) | 19.62 (10.93–28.31) |
Abbreviations: CI, confidence interval; LUAD, lung adenocarcinoma; NA, not applicable.