Table 2.
Associations of 12-month dyspnea score with 3-month patient-reported, respiratory, and cardiac outcomes
| Predictor (at 3 months) | Coefficient | P-value |
|---|---|---|
| Patient-reported outcomes | ||
| UCSD | 0.55 | < 0.001 |
| PHQ-9 | 0.36 | 0.001 |
| Pulmonary function outcomes | ||
| FVC | -0.18 | 0.14 |
| FEV1 | -0.19 | 0.11 |
| TLC | -0.13 | 0.28 |
| DLCO | -0.21 | 0.08 |
| 6MWD | -0.13 | 0.31 |
| Cardiac outcomes | ||
| BNP | 0.15 | 0.21 |
| D-dimer | 0.23 | 0.06 |
| LVEF | 0.16 | 0.19 |
| PASP | 0.18 | 0.27 |
Associations between the pre-defined predictor variables and 12-month UCSD scores were determined using multivariable linear regression models. Prespecified covariates included age, sex, and BMI
Abbreviations: UCSD University of california san diego shortness of breath questionnaire, PHQ-9 Patient health questionnaire-9, FVC Forced vital capacity, FEV1 Forced expiratory volume in the first second, TLC Total lung capacity, DLCO Diffusing capacity for carbon monoxide, 6MWD 6-min walk distance, BNP B-type natriuretic peptide, LVEF Left ventricular ejection fraction, PASP Pulmonary artery systolic pressure