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. 2023 Feb 5;13(4):1264–1285. doi: 10.7150/thno.81860

Table 2.

The surface markers of MSC-EVs, storage, and routes of administration in disease treatment.

EV source Surface markers Storage Route of administration References
hBMSCs CD90, CD44, CD105, CD73, CD63, CD81, neuropilin 1 (+)
CD34, CD45 (-)
storage at -80℃ in PBS with or without cryoprotective additives lateral ventricle injection, IV, IN 58-62
hCMSCs CD105 (+), CD90 (low), CD117 (-) storage at -80℃ in PBS with or without cryoprotective additives ND 62, 63
hUC-MSCs CD90, CD73, CD105, CD44, CD9, CD63, CD81 (+) CD45, CD34, CD11b, CD19, HLA-DR (-) storage at -80℃ in PBS with or without cryoprotective additives IV 62, 64, 65

hBMSCs, human bone marrow-derived mesenchymal stem cells; hCMSCs, human cardiac mesenchymal stromal cells; hUC-MSCs, human umbilical cord-derived MSCs; PBS, Phosphate‐buffered saline.