Table 2.
Association of each indicator and overall survival in patients with liver cancer according to cox regression models adjusted for potential confounders.
| N | Model 0 | Model 1 | Model 2 | ||||
|---|---|---|---|---|---|---|---|
| HR (95%CI) | p-value | HR (95%CI) | p-value | HR (95%CI) | p-value | ||
| HGS | |||||||
| As continues | 504 | 0.98 (0.96–0.99) | <0.001 | 0.99 (0.97–1.00) | 0.073 | 0.99 (0.97–1.01) | 0.197 |
| High HGS | 256 | Ref. | Ref. | Ref. | |||
| Low HGS | 248 | 1.90 (1.48–2.44) | <0.001 | 1.57 (1.20–2.04) | 0.001 | 1.50 (1.14–1.98) | 0.004 |
| mGPS | |||||||
| 0 | 148 | Ref. | Ref. | Ref. | |||
| 1 | 202 | 1.88 (1.36–2.61) | <0.001 | 1.42 (1.02–1.98) | 0.040 | 1.40 (1.00–1.97) | 0.055 |
| 2 | 154 | 2.48 (1.77–3.47) | <0.001 | 1.93 (1.37–2.70) | <0.001 | 1.84 (1.30–2.61) | 0.001 |
| Low mGPS (mGPS = 0) | 148 | Ref. | Ref. | Ref. | |||
| High mGPS (mGPS = 1 or 2) | 356 | 2.12 (1.57–2.86) | <0.001 | 1.58 (1.16–2.14) | 0.004 | 1.55 (1.14–2.12) | 0.001 |
| HGS-mGPS | |||||||
| Low risk (Neither) | 95 | Ref. | Ref. | Ref. | |||
| Median risk 1 (Only low HGS) | 53 | 2.13 (1.25–3.64) | 0.006 | 2.07 (1.21–3.56) | 0.008 | 2.01 (1.16–3.47) | 0.013 |
| Median risk 2 (Only high mGPS) | 161 | 2.19 (1.42–3.37) | <0.001 | 1.86 (1.20–2.86) | 0.005 | 1.84 (1.19–2.85) | 0.006 |
| High risk (Both) | 195 | 3.60 (2.38–5.44) | <0.001 | 2.49 (1.63–3.81) | <0.001 | 2.35 (1.52–3.63) | <0.001 |
Data are presented as hazard ratios (95% confidence intervals). Model 0: unadjusted. Model 1: Adjusted for age, sex, tumor stage. Model 2: Adjusted for age, sex tumor stage, surgery, radiotherapy, chemotherapy, TSF, smoking and alcohol. HGS, hand grip strength; mGPS, modified Glasgow Prognostic Score; HGS-mGPS, the combination of hand grip strength and modified Glasgow Prognostic Score. Bold values indicate statistically significant level (p < 0.05).