Table 4.
Sensitive analysis (Excluded patients who died in 180 days) (n = 413).
| N | Model 0 | Model 1 | Model 2 | ||||
|---|---|---|---|---|---|---|---|
| HR (95%CI) | p-value | HR (95%CI) | p-value | HR (95%CI) | p-value | ||
| HGS | |||||||
| As continues | 413 | 0.98 (0.97–1.00) | 0.051 | 0.99 (0.97–1.01) | 0.236 | 0.99 (0.97–1.01) | 0.192 |
| High HGS | 227 | Ref. | Ref. | Ref. | |||
| Low HGS | 186 | 1.71 (1.26–2.31) | <0.001 | 1.44 (1.05–1.98) | 0.023 | 1.55 (1.11–2.17) | 0.010 |
| mGPS | |||||||
| 0 | 113 | Ref. | Ref. | Ref. | |||
| 1 | 163 | 1.94 (1.31–2.86) | 0.001 | 1.47 (0.99–2.19) | 0.056 | 1.36 (0.91–2.04) | 0.132 |
| 2 | 117 | 2.42 (1.61–3.64) | <0.001 | 1.93 (1.28–2.90) | 0.002 | 1.99 (1.31–3.02) | 0.001 |
| Low mGPS (mGPS = 0) | 133 | Ref. | Ref. | Ref. | |||
| High mGPS (mGPS = 1 or 2) | 280 | 2.13 (1.49–3.04) | <0.001 | 1.65 (1.14–2.37) | 0.007 | 1.86 (1.29–2.68) | 0.001 |
| HGS-mGPS | |||||||
| Low risk (Neither) | 89 | Ref. | Ref. | Ref. | |||
| Median risk 1 (Only low HGS) | 44 | 1.91 (1.01–3.61) | 0.046 | 1.86 (0.98–3.54) | 0.057 | 2.02 (1.05–3.87) | 0.035 |
| Median risk 2 (Only high mGPS) | 138 | 2.23 (1.36–3.63) | 0.001 | 1.87 (1.14–3.06) | 0.013 | 1.79 (1.09–2.94) | 0.022 |
| High risk (Both) | 142 | 3.26 (2.02–5.27) | <0.001 | 2.30 (1.40–3.87) | 0.001 | 2.34 (1.42–3.87) | 0.001 |
Data are presented as hazard ratios (95% confidence intervals). Model 0: unadjusted. Model 1: Adjusted for age, gender, tumor stage. Model 2: Adjusted for age, sex tumor stage, surgery, radiotherapy, chemotherapy, TSF, smoking and alcohol. HGS, handgrip strength; mGPS, modified Glasgow Prognostic Score; HGS-mGPS, combination of HGS and mGPS; HR, hazard ratio; CI, confidence interval; p, probability. Bold values indicate statistically significant level (p < 0.05).