Figure 1.

Syrian Hamster Tumor Models. (A) Syngeneic tumor models involve the transplantation of in vitro cultured Syrian hamster cancer cells into immunocompetent Syrian hamsters. (B) Carcinogenic tumor models are induced by carcinogens, which allows tumors to undergo de novo formation. (C) Human xenograft tumor models utilize human cancer cells to inject into immunocompromised Syrian hamsters or the cheek pouches of immunocompetent Syrian hamsters. (D) Genetically engineered models are the application of genetic engineering techniques to modify hamster genes to induce cancer development.