Table 2.

The AUC of JAK2V617F allele burden and WT1 expression for MPN subgroups.

Group	Gene	AUC (95% Confidence Intervals)	P	Se (%)	Sp (%)	Cut-Off Value
ET vs PV	JAK2V617F	0.943 (.891–.995)	<0.01	96.15	86.67	47.09%
	WT1	0.744 (.615–.873)	<0.01	57.69	88.89	0.34
	Combination of JAK2V617F and WT1	0.956 (.916–1.000)	<0.01	96.15	86.67
ET vs PMF	JAK2V617F	0.869 (.766–.973)	<0.01	73.68	86.67	46.33%
	WT1	0.844 (.724–.965)	<0.01	73.68	88.89	0.33
	Combination of JAK2V617F and WT1	0.871 (.768–.975)	<0.01	68.42	100
PV vs PMF	JAK2V617F	0.555 (.356–.754)	0.54	47.37	84.62	86.84%
	WT1	0.665 (.498–.832)	0.06	42.11	96.15	1.335
	Combination of JAK2V617F and WT1	0.737 (.578–.897)	<0.01	63.16	84.62

Abbreviation: Se: Sensitivity; Sp: Specificity; AUC: area under the curve.