Table 4.

Longitudinal association of depressive symptoms with 24-h activity rhythms and sleep over time

	B	95% CI	β	p value
IS
IS	−0.001	−0.002 to 0.000	−0.008	0.021
IS × time	0.000	0.000–0.000	−0.001	0.32
IV
IV	0.002	0.001–0.003	0.016	<0.001
IV × time	0.000	0.000 to −0.000	−0.002	0.025
TIB
TIB	0.009	0.004–0.015	0.011	0.001
TIB × time	0.000	−0.001 to 0.001	0.000	0.88
TST
TST	−0.006	−0.012 to 0.000	−0.006	0.06
TST × time	0.002	0.001–0.003	0.002	<0.001
SE
SE	−0.140	−0.196;−0.084	−0.017	<0.001
SE × time	0.022	0.011;0.033	0.003	<0.001
SOL
SOL	0.013	0.008;0.018	0.018	<0.001
SOL × time	−0.001	−0.002;0.000	−0.002	0.046
WASO
WASO	0.161	−0.012;0.334	0.006	0.07
WASO × time	−0.040	−0.072;−0.008	−0.002	0.015
Self-rated sleep quality score
Sleep quality	0.193	0.171;0.215	0.056	<0.001
Sleep quality × time	−0.014	−0.019;−0.009	−0.004	<0.001

TST, total sleep time; TIB, time in bed; SE, sleep efficiency; WASO, wake after sleep onset; SOL, sleep onset latency; IS, interdaily stability; IV, intradaily variability; CI, confidence interval for B.

B is the effect estimate of the determinant and β is the standardized effect estimate of the determinant. Effect estimates were obtained using linear-mixed models, adjusted for age, sex, cohort, actigraphy device at follow-up, employment, education, partnership, smoking, alcohol consumption, coffee intake, and BMI (model 2). Estimates should be interpreted as changes in the log-transformed depressive symptoms score. Multiple testing-corrected p value = 0.00625.