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. 2023 Feb 28;11(4):179. doi: 10.21037/atm-23-400

Table 2. The results of the feature selection in the competing risk model.

Levels Factor Univariate analysis Multivariate analysis
HR (95% CI) P HR (95% CI) P
Age >80 years Age 1.79 (1.79–2.6) 0.0020 1.86 (1.28–2.7) 0.0012
Age 60–80 years Age 1.22 (1.22–1.61) 0.1400 1.18 (0.9–1.55) 0.2400
Age unknown Age 24.59 (24.59–31.57) 0.0000 20.31 (12.78–32.26) 0.0000
Behavior SCC Behavior 1.77 (1.77–3.09) 0.0440 1.76 (1.01–3.07) 0.0470
Behavior SCC, keratinizing Behavior 1.75 (1.75–3.21) 0.0730 1.8 (0.98–3.3) 0.0570
Behavior SCC, non-keratinizing Behavior 0.93 (0.93–2.16) 0.8600 0.92 (0.4–2.16) 0.8600
Bone metastasis: yes Bone metastasis 3.26 (3.26–5.52) 0.0000 3.35 (1.94–5.79) 0.0000
Chemotherapy: yes Chemotherapy 1 (1–1.26) 0.9700
Grade: Grade II Grade 0.88 (0.88–1.55) 0.6500
Grade: Grade III Grade 0.89 (0.89–1.58) 0.6800
Grade: Grade IV Grade 0.31 (0.31–2.43) 0.2700
Grade: unknown Grade 0.72 (0.72–1.31) 0.2900
Income > $60,000 Income 1.01 (1.01–1.6) 0.9700
Income $40,000–$60,000 Income 0.92 (0.92–1.5) 0.7300
Liver metastasis: yes Liver metastasis 1.89 (1.89–4.03) 0.0980
Lung metastasis: unknown Lung metastasis 1.15 (1.15–8.46) 0.8900
Lung metastasis: yes Lung metastasis 1.59 (1.59–2.52) 0.0510
Marital status: married Marital status 0.93 (0.93–1.31) 0.6800
Marital status: other Marital status 0.54 (0.54–1.08) 0.0810
Marital status: separated Marital status 0.65 (0.65–2.14) 0.4800
Marital status: single Marital status 0.96 (0.96–1.41) 0.8500
Marital status: widowed Marital status 1.3 (1.3–2.01) 0.2400
Months treatment: >3 Months treatment 0.83 (0.83–1.3) 0.4100
Months treatment: unknown Months treatment 1.1 (1.1–1.59) 0.6200
Nodes metastasis: unknown Nodes metastasis 0.77 (0.77–0.99) 0.0440
Nodes metastasis: yes Nodes metastasis 0.77 (0.77–3.18) 0.7200
Nodes positive: yes Nodes positive 1.57 (1.57–2.07) 0.0017
Nodes removed: yes Nodes removed 0.79 (0.79–1.11) 0.1700
N* staging: N1 N stage 1.57 (1.57–2.32) 0.0220
N* staging: N2 N stage 1.84 (1.84–2.52) 0.0001
N* staging: N3 N stage 1.61 (1.61–2.96) 0.1200
N* staging: NX N stage 1.68 (1.68–2.56) 0.0150
Number of malignant: >3 Number of malignant 0.23 (0.23–0.93) 0.0390
Primary site: other Primary site 2.54 (2.54–4.71) 0.0030 2.34 (1.25–4.38) 0.0078
Primary site: PS Primary site 1.97 (1.97–3.64) 0.0310 1.79 (0.96–3.33) 0.0680
Primary site: PWH Primary site 1.96 (1.96–4.06) 0.0710 1.8 (0.87–3.75) 0.1200
Primary: yes Primary 1.27 (1.27–1.66) 0.0910
Race: black Race 0.5 (0.5–0.83) 0.0080 0.56 (0.33–0.95) 0.0330
Race: other Race 0.71 (0.71–2.08) 0.5400 0.87 (0.29–2.59) 0.8000
Race: white Race 0.71 (0.71–1.04) 0.0780 0.78 (0.52–1.17) 0.2200
Radiation: yes Radiation 0.9 (0.9–1.18) 0.4500
Sex: male Sex 0.93 (0.93–1.24) 0.6200
Size: >6 cm Size 1.51 (1.51–2.42) 0.0820 1.54 (0.96–2.45) 0.0720
Size: 3–6 cm Size 2.39 (2.39–4.03) 0.0011 2.3 (1.37–3.87) 0.0017
Stage group II Stage group II 0.91 (0.91–2.35) 0.8500
Stage group III Stage group III 1.64 (1.64–3.84) 0.2500
Stage group IV Stage group IV 2.31 (2.31–5.14) 0.0400
Stage group II: unknown Stage group II 1.89 (1.89–4.38) 0.1400
Summary stage: localized Summary stage 0.41 (0.41–0.63) 0.0000
Summary stage: regional Summary stage 0.79 (0.79–1.01) 0.0600
Surgery radiation sequence: 2 Radiation after surgery 0.83 (0.83–2.02) 0.6900
Surgery radiation sequence: 3 No radiation 0.79 (0.79–1.88) 0.6000
Surgery radiation sequence: other Other 0.85 (0.85–6.89) 0.8800
Surgery: yes Surgery 0.82 (0.82–1.1) 0.1900
Systemic therapy: yes Systemic therapy 1.12 (1.12–1.48) 0.4000
T* staging: T2 T stage 1.57 (1.57–2.76) 0.1200
T* staging: T3 T stage 1.92 (1.92–3.41) 0.0270
T* staging: T4 T stage 2.36 (2.36–4.12) 0.0025
T* staging: TX T stage 1.14 (1.14–2.42) 0.7300
T* staging: unknown T stage 2.02 (2.02–3.74) 0.0250

*, TNM staging, TNM groups by 7th edition of the American Joint Committee on Cancer Classifications. SCC, sequamous-cell carcinoma; PS, pyriform sinus; PWH, posterior wall of hypopharynx.