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. 2023 Feb 28;11(4):163. doi: 10.21037/atm-22-6481

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2023 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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Comparison of lncRNA expression profiles between HNSCC tumor samples and normal samples. (A) Heatmap of differentially expressed lncRNA in normal and tumor tissue. Differentially expressed lncRNA are lncRNA show an adjusted P value ≤0.0001. Genes shown in red are upregulated and genes in blue are downregulated. (B) The significantly upregulated and downregulated lncRNA in HNSCC tumor samples and normal samples are shown in the volcano plot (log₂ fold change >1.0, P<0.01). HNSCC, head and neck squamous cell carcinoma; lncRNA, long noncoding RNA.