ChEMBL |
https://www.ebi.ac.uk/chembl/ |
A manually curated database of bioactive molecules with drug-like properties. It gathers chemical, bioactivity, and genomic data to aid the translation of genomic information into effective new drugs. |
Mendez et al.7
|
ChemDB |
http://cdb.ics.uci.edu |
A chemical database that contains nearly 5 million commercially available small molecules, along with their predicted or experimentally determined physicochemical properties. |
Chen et al.8
|
COCONUT |
https://coconut.naturalproducts.net/ |
A database that contains 407,270 unique natural products, along with information about their molecular properties and molecular descriptors. |
Sorokina et al.9
|
DGIdb |
http://www.dgidb.org |
A database that provides information on DTI and druggable genomes from over 30 trusted sources. |
Freshour et al.10
|
DrugBank |
http://www.drugbank.ca |
A database of drugs, their targets, 3D structures, and other useful information. |
Wishart et al.11
|
DTC |
http://drugtargetcommons.fimm.fi/ |
A crowd-sourcing platform that provides drug-target bioactivity data and classification of targets. |
Tang et al.12
|
INPUT |
http://cbcb.cdutcm.edu.cn/INPUT/ |
A network pharmacology platform for traditional Chinese medicine. It contains 29,812 compounds isolated from 4,716 Chinese herbs. |
Li et al.13
|
PubChem |
https://pubchem.ncbi.nlm.nih.gov/ |
An open chemistry database that provides information about molecules, such as chemical structures, identifiers, chemical and physical properties, and biological activities. |
Kim et al.14
|
SIDER |
http://sideeffects.embl.de |
A database that provides information on marketed medicines and their recorded adverse reactions. |
Campillos et al.15
|
STITCH |
http://stitch.embl.de/ |
A database of known and predicted interactions between chemicals and proteins, including 9,643,763 proteins from 2,031 organisms. |
Szklarczyk et al.16
|