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. Author manuscript; available in PMC: 2023 Mar 13.
Published in final edited form as: Cell Metab. 2023 Mar 7;35(3):429–437.e5. doi: 10.1016/j.cmet.2023.02.005

Figure 4. FGF21 is a physiologic regulator of noradrenergic neurons.

Figure 4.

(A) Representative confocal images of immunostaining for c-Fos (white) and norepinephrine transporter (NET; green) in locus coeruleus sections prepared from wild-type (WT) and Fgf21−/− mice 2.5 hours after oral gavage with either water or ethanol (5 g/kg). Scale bar represents 50 μM.

(B) Quantification of c-Fos/NET co-expression (upper panel) and total NET-positive cell number (lower panel) (n = 3 sections/mouse, 4 mice/group). Data represent the mean ± SEM. Different lowercase letters indicate statistical significance (P < 0.05) by two-way ANOVA.