Table 5.
Mean (±standard deviation) Dice similarity coefficient (DSC) [or generalized DSC (GDSC) of all labels] and mean surface distance (MSD) between automatic and manual segmentations of the ablation experiments in the unseen datasets, testing for generalizability. For better interpretation, background color of each cell indicates the relative performance compared to the best (darkest red) and worst (darkest blue) performance in each row (the darker red/blue, the closer to the best/worst performance respectively).
| w/o fine-tuning subnet | w/o weighted voting subnet | w/o atlas mask | DLF | ||
|---|---|---|---|---|---|
| Dice similarity coefficient | Brain-7T-T2 dataset | ||||
| GDSC | 61.3±6.9 | 61.4±10.5 | 70.7±3.8 | 71.2±4.3 | |
| Hippo | 81.0±9.2 | 81.7±13.2 | 90.8±1.4 | 90.7±1.5 | |
| CA1 | 58.8±14.9 | 65.0±13.4 | 75.5±3.4 | 75.5±3.9 | |
| CA2 | 38.1±24.5 | 57.0±14.0 | 67.1±6.4 | 67.8±6.4 | |
| CA3 | 49.1±16.5 | 56.4±15.5 | 69.3±5.5 | 69.6±5.6 | |
| DG | 67.2±18.4 | 70.3±15.0 | 80.9±2.0 | 80.6±2.6 | |
| SUB | 71.9±6.7 | 67.8±9.7 | 72.0±5.4 | 73.4±5.7 | |
| TAIL | 73.7±5.6 | 68.5±13.9 | 80.5±2.8 | 80.4±3.3 | |
| ERC | 68.8±8.7 | 61.6±18.8 | 80.2±5.0 | 79.5±5.7 | |
| BA35 | 54.4±10.1 | 56.3±14.6 | 65.2±9.5 | 66.0±9.8 | |
| BA36 | 57.0±10.3 | 56.3±15.5 | 66.2±7.9 | 67.5±8.7 | |
| PHC | 66.6±6.5 | 69.1±11.3 | 72.8±9.3 | 72.4±8.2 | |
| Lumbar-Healthy dataset | |||||
| Lumbar | 79.9±5.6 | 78.1±5.9 | 83.0±4.7 | 83.4±4.7 | |
| Mean surface distance (mm) | Brain-7T-T2 dataset | ||||
| Hippo | 0.65±0.26 | 0.70±0.58 | 0.38±0.06 | 0.38±0.06 | |
| CA1 | 0.91±0.38 | 1.16±1.36 | 0.63±0.11 | 0.61±0.09 | |
| CA2 | 1.73±1.91 | 0.88±0.87 | 0.56±0.14 | 0.54±0.13 | |
| CA3 | 1.17±0.93 | 1.05±1.13 | 0.55±0.11 | 0.54±0.11 | |
| DG | 0.77±0.42 | 0.97±1.09 | 0.55±0.07 | 0.57±0.09 | |
| SUB | 0.78±0.23 | 0.93±0.30 | 0.84±0.21 | 0.78±0.16 | |
| TAIL | 0.69±0.12 | 0.94±0.67 | 0.57±0.09 | 0.57±0.09 | |
| ERC | 0.82±0.20 | 1.13±0.88 | 0.61±0.18 | 0.60±0.19 | |
| BA35 | 1.10±0.28 | 1.15±0.68 | 0.95±0.27 | 0.94±0.28 | |
| BA36 | 1.31±0.33 | 1.38±0.69 | 1.09±0.21 | 1.05±0.22 | |
| PHC | 0.92±0.28 | 0.78±0.26 | 0.83±0.31 | 0.87±0.32 | |
| Lumbar-Healthy dataset | |||||
| Lumbar | 2.63±0.46 | 2.44±0.37 | 2.16±0.50 | 2.12±0.50 | |
Abbreviations: DLF = deep label fusion; Hippo = hippocampus; AHippo/PHippo = anterior/posterior hippocampus; CA1–3 = cornu ammonis 1 to 3; dentate gyrus = DG; subiculum = SUB; TAIL = the tail of hippocampus; ERC = entorhinal cortex; BA35/36 = Brodmann areas 35/36; PHC = parahippocampal cortex; w/ and w/o = with and without.