TABLE 3.
Genotype distribution and frequency of alleles and its relationship with non‐ISR and ISR
| Non‐ISR | ISR | p | Univariate regression (odds ratio 95% CI) | Multivariate regression (odds ratio 95% CI) | |||||
|---|---|---|---|---|---|---|---|---|---|
| N (%) | N (%) | Non‐ISR | ISR | p | Non‐ISR | ISR | p | ||
| Rs1748195 | 0.829 | ||||||||
| AA | 29 (33.3) | 15 (37.5) | Ref | Ref | Ref | Ref | |||
| AC | 44 (50.6) | 20 (50) | Ref | 0.88 (0.39, 1.99) | 0.757 | Ref | 0.56 (0.20, 1.54) | 0.262 | |
| CC | 14 (16.1) | 5 (12.5) | Ref | 0.69 (0.21, 2.28) | 0.544 | Ref | 0.42 (0.09, 1.97) | 0.272 | |
| Dominant | 0.647 | ||||||||
| AA | 29 (33.3) | 15 (37.5) | Ref | Ref | Ref | Ref | |||
| AC + CC | 58 (66.7) | 25 (62.5) | Ref | 0.83 (0.38, 1.82) | 0.647 | Ref | 0.53 (0.20, 1.39) | 0.195 | |
| Recessive | 0.598 | ||||||||
| AA + AC | 73 (83.9) | 35 (87.5) | Ref | Ref | Ref | Ref | |||
| CC | 14 (16.1) | 5 (12.5) | Ref | 0.74 (0.25, 2.23) | 0.599 | Ref | 0.59 (0.14, 2.44) | 0.466 | |
| Additive | 0.543 | ||||||||
| AA | 29 (67.4) | 15 (75) | Ref | Ref | Ref | Ref | |||
| CC | 14 (32.6) | 5 (25) | Ref | 0.69 (0.21, 2.28) | 0.544 | Ref | 0.40 (0.08, 2.02) | 0.270 | |
| Codominant | 0.952 | ||||||||
| AA + CC | 43 (49.4) | 20 (50) | Ref | Ref | Ref | Ref | |||
| CC | 44 (50.6) | 20 (50) | Ref | 0.98 (0.46, 2.07) | 0.952 | Ref | 0.71 (0.28, 1.79) | 0.464 | |