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. 2023 Mar 13;56:11. doi: 10.1186/s40659-023-00423-8

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© The Author(s) 2023

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Masson trichrome-stained pancreas sections of A; Sham group showed minimal green color of collagen fibers in between the closely packed pancreatic acini, B; NAFP group showed marked green collagen fibers deposition in the interlobular septa and in between the destructed acini, C; R-10 group collagen fibers deposition in the interlobular septa and in between the destructed acini, D; R-20 group showed collagen fibers especially around blood vessels and distorted acini, and E; R-30 group showed mild collagen fibers deposition around acini. [Magnification: 200x]. F The mean area % of collagen deposition (± SD) in the Sham and the experimental groups (n = 6): ^*P < 0.001 vs the Sham group; ^###P < 0.001, and ^##P < 0.01 vs NAFP group. ^aP < 0.05 vs R-10. ^bP < 0.05 vs R-20. Measurements were taken from three different sections obtained from each animal. Moreover, five haphazardly selected non-overlapping fields were examined for each section