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. Author manuscript; available in PMC: 2023 Mar 13.
Published in final edited form as: Neurobiol Dis. 2022 Dec 16;177:105967. doi: 10.1016/j.nbd.2022.105967

Fig. 1.

Fig. 1.

APP/PS1 mice do not consume more ethanol than control mice. a) Timeline for the experimental protocol. b) Cumulative and average weekly EtOH intake (g/kg) from the 10-week plotted as a function of genotype. APP/PS1 mice did not consume more EtOH than wildtype mice. c) Cumulative and average weekly EtOH preference (% total fluid) from the 10-week exposure period plotted as a function of genotype. No difference between wildtype and APP/PS1 mice was observed (unpaired t-test). d) Cumulative and average weekly water consumption across the 10-week EtOH exposure in EtOH-treated mice. No difference was seen in EtOH-treated wildtype or APP/PS1 mice (unpaired t-test). e) Cumulative and average weekly water consumption across the 10-week EtOH exposure period in water-treated mice. APP/PS1 mice consumed more water than wildtype mice (p < 0.0001, unpaired t-test). Wildtype + H2O, n = 10; APP/PS1 + H2O, n = 9; Wildtype + EtOH, n = 7; APP/PS1 + EtOH, n = 8. ***p < 0.001.