| 1.1 Postoperative intraocular pressure (IOP) at 1 year by device type |
6 |
|
Mean Difference (IV, Random, 95% CI) |
Subtotals only |
| 1.1.1 Ex‐PRESS + trab versus trab |
5 |
213 |
Mean Difference (IV, Random, 95% CI) |
‐1.76 [‐2.81, ‐0.70] |
| 1.1.2 PreserFlo MicroShunt versus trab |
1 |
446 |
Mean Difference (IV, Random, 95% CI) |
3.20 [2.29, 4.11] |
| 1.2 Change in IOP from baseline at 1 year |
1 |
|
Mean Difference (IV, Random, 95% CI) |
Totals not selected |
| 1.3 Postoperative IOP at 6 months by device type |
6 |
|
Mean Difference (IV, Random, 95% CI) |
Subtotals only |
| 1.3.1 Ex‐PRESS + trab versus trab |
5 |
253 |
Mean Difference (IV, Random, 95% CI) |
‐0.10 [‐1.40, 1.20] |
| 1.3.2 PreserFlo MicroShunt versus trab |
1 |
446 |
Mean Difference (IV, Random, 95% CI) |
3.00 [1.62, 4.38] |
| 1.4 Postoperative IOP at 2 years |
3 |
212 |
Mean Difference (IV, Random, 95% CI) |
‐1.38 [‐2.66, ‐0.09] |
| 1.5 Change in IOP from baseline at 6 months |
1 |
20 |
Mean Difference (IV, Random, 95% CI) |
0.20 [‐5.46, 5.86] |
| 1.6 Postoperative logMAR best‐corrected visual acuity at 1 year |
3 |
110 |
Mean Difference (IV, Random, 95% CI) |
‐0.04 [‐0.19, 0.10] |
| 1.7 Proportion of participants who are drop‐free at 1 year by device type |
3 |
|
Risk Ratio (M‐H, Random, 95% CI) |
Subtotals only |
| 1.7.1 Ex‐PRESS + trab versus trab |
2 |
48 |
Risk Ratio (M‐H, Random, 95% CI) |
2.04 [0.42, 9.82] |
| 1.7.2 PreserFlo MicroShunt versus trab |
1 |
509 |
Risk Ratio (M‐H, Random, 95% CI) |
0.84 [0.77, 0.93] |
| 1.8 Mean number of IOP lowering medications at 1 year by device type |
4 |
|
Mean Difference (IV, Random, 95% CI) |
Subtotals only |
| 1.8.1 Ex‐PRESS + trab versus trab |
3 |
170 |
Mean Difference (IV, Random, 95% CI) |
‐0.34 [‐0.62, ‐0.07] |
| 1.8.2 PreserFlo MicroShunt versus trab |
1 |
509 |
Mean Difference (IV, Random, 95% CI) |
0.30 [0.11, 0.49] |
| 1.9 Proportion of participants with IOP less than 5 mmHg (hypotony) or shallow anterior chamber by device type |
7 |
868 |
Risk Ratio (M‐H, Random, 95% CI) |
0.73 [0.46, 1.17] |
| 1.9.1 Ex‐PRESS + trab versus trab |
6 |
342 |
Risk Ratio (M‐H, Random, 95% CI) |
0.92 [0.61, 1.39] |
| 1.9.2 PreserFlo MicroShunt versus trab |
1 |
526 |
Risk Ratio (M‐H, Random, 95% CI) |
0.44 [0.25, 0.79] |
| 1.10 Proportion of participants with bleb leakage by device type |
6 |
840 |
Risk Ratio (M‐H, Random, 95% CI) |
0.64 [0.40, 1.02] |
| 1.10.1 Ex‐PRESS + trab versus trab |
5 |
314 |
Risk Ratio (M‐H, Random, 95% CI) |
0.99 [0.45, 2.16] |
| 1.10.2 PreserFlo MicroShunt versus trab |
1 |
526 |
Risk Ratio (M‐H, Random, 95% CI) |
0.51 [0.28, 0.90] |
| 1.11 Proportion of participants with reoperations for glaucoma by device type |
5 |
720 |
Risk Ratio (M‐H, Random, 95% CI) |
0.69 [0.24, 1.98] |
| 1.11.1 Ex‐PRESS + trab versus trab |
4 |
194 |
Risk Ratio (M‐H, Random, 95% CI) |
0.34 [0.09, 1.26] |
| 1.11.2 PreserFlo MicroShunt versus trab |
1 |
526 |
Risk Ratio (M‐H, Random, 95% CI) |
1.30 [0.77, 2.22] |
| 1.12 Proportion of participants with cataract extraction by device type |
5 |
820 |
Risk Ratio (M‐H, Random, 95% CI) |
0.46 [0.27, 0.80] |
| 1.12.1 Ex‐PRESS + trab versus trab |
4 |
294 |
Risk Ratio (M‐H, Random, 95% CI) |
0.34 [0.14, 0.80] |
| 1.12.2 PreserFlo MicroShunt versus trab |
1 |
526 |
Risk Ratio (M‐H, Random, 95% CI) |
0.57 [0.28, 1.17] |
| 1.13 Proportion of participants with endophthalmitis |
1 |
120 |
Risk Ratio (M‐H, Random, 95% CI) |
0.34 [0.01, 8.29] |
| 1.14 Proportion of participants with loss of vision of > 2 lines or loss of light perception |
1 |
526 |
Risk Ratio (M‐H, Random, 95% CI) |
0.57 [0.30, 1.07] |
