TABLE 3.
Group B meningococcus bactericidal assaya
| MAb | IgG concn (μg/ml) | Bactericidal titer | LC50b (μg/ml) |
|---|---|---|---|
| A74 | 1,200 | 1,024 | 1.2 |
| A79 | 1,000 | 4,096 | 0.24 |
| A98 | 1,400 | 1,024 | 1.4 |
| 30H12 | 4,000 | 32,768 | 0.12 |
a
The bactericidal titer was expressed as the reciprocal of the highest dilution of the antibody tested at which 50% or more of the bacteria were killed. The A74, A79, and A98 and 30H12 antibodies exhibited a high level of bactericidal activity against the group B meningococcus.
b
LC50, lowest concentration killing 50% of bacteria.