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CXCR4 inhibitor affects the TME. Increased gene expression scores for IFNγ (A) and TIS (B) as determined by NanoString analysis of RNA extracted from patient biopsy samples at predose and post-mavorixafor timepoints. Gene expression scores for antigen processing and presentation genes as determined by NanoString analysis for 9 patients receiving Mavorixafor monotherapy (C). Data shown are from all evaluable patient samples available at the time of analyses.
