TABLE 6.
Plasma atorvastatin and its metabolite concentrations-linear regression model coefficients.
| Variable | Effect (β) | p-value | R 2 |
|---|---|---|---|
| 2-AT+2-ATL | |||
| Glucose | −0.019 | 0.025 | |
| LP(a) | 2.00E-04 | 0.083 | |
| ABCC4 rs3742106 | −0.162 | 0.028 | |
| ABCC4 rs868853 | 0.177 | 0.011 | |
| NR1I2 rs6785049 | 0.123 | 0.044 | 0.14 |
| AT+2-AT+4-AT | |||
| ApoAⅠ | 0.352 | 0.001 | |
| ALB | −0.013 | 0.006 | |
| Glucose | −0.021 | 0.026 | |
| eGFR | −0.004 | 0.016 | |
| ABCC4 rs3742106CC | −0.212 | 0.028 | |
| ABCC4 rs3742106AC | −0.029 | 0.723 | 0.19 |
Notes: bold fonts indicates p < 0.05.
Adjusted for gender, age, smoking and alcohol consumption.
LP(a), lipoprotein (a); ApoAⅠ, Apolipoprotein AI; ALB, albumin; eGFR, estimated glomerular filtration rate.