Table 4.
Horizontal pleiotropy analysis for IVs of 8 GM taxa associated with focal epilepsy.
Exposure | MR-Egger intercept test | MR-PRESSO global test | |||
---|---|---|---|---|---|
Egger_intercept | SE | p-value | RSS obs | p-value | |
Phylum | |||||
Verrucomicrobia (ID: 3982) | 0.023 | 0.054 | 0.678 | 13.273 | 0.450 |
Class | |||||
Verrucomicrobiae (ID: 4029) | 0.039 | 0.068 | 0.581 | 13.605 | 0.379 |
Order | |||||
Verrucomicrobiales (ID: 4030) | 0.039 | 0.068 | 0.581 | 13.605 | 0.364 |
Family | |||||
Verrucomicrobiaceae(ID: 4036) | 0.039 | 0.068 | 0.579 | 13.610 | 0.341 |
Genus | |||||
Akkermansia (ID: 4037) | 0.039 | 0.068 | 0.579 | 13.608 | 0.364 |
Alloprevotella (ID: 961) | −0.070 | 0.217 | 0.768 | 1.914 | 0.895 |
Clostridium Sensu Stricto 1(ID: 1873) | 0.137 | 0.078 | 0.138 | 12.978 | 0.187 |
Sutterella (ID: 2896) | −0.098 | 0.069 | 0.187 | 12.428 | 0.525 |
SE, standard error; RSS, residual sum of squares.