Table 4.

Horizontal pleiotropy analysis for IVs of 8 GM taxa associated with focal epilepsy.

Exposure	MR-Egger intercept test			MR-PRESSO global test
	Egger_intercept	SE	p-value	RSS obs	p-value
Phylum
Verrucomicrobia (ID: 3982)	0.023	0.054	0.678	13.273	0.450
Class
Verrucomicrobiae (ID: 4029)	0.039	0.068	0.581	13.605	0.379
Order
Verrucomicrobiales (ID: 4030)	0.039	0.068	0.581	13.605	0.364
Family
Verrucomicrobiaceae(ID: 4036)	0.039	0.068	0.579	13.610	0.341
Genus
Akkermansia (ID: 4037)	0.039	0.068	0.579	13.608	0.364
Alloprevotella (ID: 961)	−0.070	0.217	0.768	1.914	0.895
Clostridium Sensu Stricto 1(ID: 1873)	0.137	0.078	0.138	12.978	0.187
Sutterella (ID: 2896)	−0.098	0.069	0.187	12.428	0.525

SE, standard error; RSS, residual sum of squares.