Common and sex-specific metabolites in different tissues in response to fasting. (A) A heat map of changed metabolites in two tissues and more in response to fasting in either males or females. (B) A heat map of tissue-specific changes of metabolites in response to fasting in either males or females. GSSG, oxidized glutathione; C11-Car, 4,8-dimethylnonanoylcarnitine; C2-Car, L-acetylcarnitine; NMA, N1-methylnicotinamide; G1P, glucose-1-phosphate; DHAP, dihydroxyacetone phosphate; G6P, glucose-6-phosphate; D-2HG, D-2-hydroxyglutarate.