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. 2023 Mar 8;43(10):1845–1857. doi: 10.1523/JNEUROSCI.1259-22.2023

Figure 6.

Figure 6.

Neuronal deletion of SIRT3 results in female-specific working spatial memory impairment. Y-maze assessment of spatial working memory in mice at (A) 6 months of age (n = 11-19/group, 2 cohorts), (B) 12 months of age (n = 11-17/group, 3 cohorts), and (C) on inducible neuronal SIRT3 deletion (n = 6-12/group, 4 cohorts). Locomotion assessment, measured by total arm entries in mice at (D) 12 months of age (n = 11-17/group) and (E) on inducible neuronal SIRT3 deletion (n = 6-12/group, 4 cohorts). *p < 0.05 (two-way ANOVA followed by Sidak's multiple comparison test). Error bars indicate mean ± SEM.