Table 2.

Percent inhibition of baseline synaptic transmission at the Im-BLA(NAc-projecting) synapse by peptides, alone and in the presence of peptidase inhibitors

Group	Nociceptin	Nociceptin + thiorphan
Control (morphine-free bath)	19.61 ± 11.65 (7)	34.34 ± 18.21* (7)
Morphine withdrawal	2.89 ± 5.88 (6)	35.53 ± 12.81* (6)

Values are mean inhibition of eEPSC amplitude from baseline (%) ± SEM. Neuron number for each group is shown in brackets. Data were analyzed using two-way repeated measures ANOVAs with post hoc Bonferroni's multiple comparisons tests to assess the effects of peptidase inhibition on the ability of nociceptin to inhibit the Im-BLA(NAc-projecting) synapse in control and withdrawal.

*, significant results from post hoc Bonferroni's tests (p < 0.05) comparing precent inhibition produced by nociceptin alone with percent inhibition produced by nociceptin + thiorphan for each group.