Abstract
We report a case of HLA B27 negative Crohn's spondylitis with a detailed study of the proband's family, including tissue types of all living relatives. The family included cases of psoriasis, psoriatic spondylitis, and idiopathic ankylosing spondylitis. We believe this to be the first report of these associated diseases occurring in one family. All relatives were B27 negative, including one with psoriatic spondylitis. The aetiological implications of these findings are considered.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Bennett R., Bywaters E. G., Holt P. J. Familial spondylitis. Proc R Soc Med. 1971 Jun;64(6):663–664. [PMC free article] [PubMed] [Google Scholar]
- SHERLOCK P., BELL B. M., STEINBERG H., ALMY T. P. FAMILIAL OCCURRENCE OF REGIONAL ENTERITIS AND ULCERATIVE COLITIS. Gastroenterology. 1963 Sep;45:413–420. [PubMed] [Google Scholar]
- Woodrow J. C., Eastmond C. J. HLA B27 and the genetics of ankylosing spondylitis. Ann Rheum Dis. 1978 Dec;37(6):504–509. doi: 10.1136/ard.37.6.504. [DOI] [PMC free article] [PubMed] [Google Scholar]