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. Author manuscript; available in PMC: 2023 Mar 13.
Published in final edited form as: J Am Chem Soc. 2022 Dec 13;144(51):23668–23676. doi: 10.1021/jacs.2c11223

Scheme 1.

Scheme 1.

Small-molecule scaffolds with NIR-II fluorescence. (a) Previous molecules which possess NIR-II fluorescence. (b) The schematic diagram of BF2 formazanate dyes penetrating the BBB from the circulation.