Table 3.
33 Factorial design Uncaria tomentosa FDOFs. With dependent and independent variables.
| F. Code | Independent variable |
Dependant variable |
|||
|---|---|---|---|---|---|
| X1 (Polymer) | X2 (Plasticiser) | X3 (Superdisintigrant) | Y1 (Folding endurance) | Y2 (Disintegration time in sec) | |
| F1 | Pullulan gum | Propylene glycol | Cross Povidone | 170.5 ± 11.6 | 41.2 ± 1.26 |
| F2 | Maltodextrin | Propylene glycol | Cross Povidone | 205.6 ± 13.6 | 52.3 ± 2.31 |
| F3 | HPMC | Propylene glycol | Cross Povidone | 190.4 ± 15.5 | 48.1 ± 2.54 |
| F4 | PVA | Propylene glycol | Cross Povidone | 165.5 ± 12.4 | 56.5 ± 2.95 |
| F5 | Pullulan gum | PEG 400 | Croscarmellose sodium | 215.2 ± 13.9 | 35.9 ± 0.58 |
| F6 | Maltodextrin | PEG 400 | Croscarmellose sodium | 210.3 ± 11.2 | 59.7 ± 3.65 |
| F7 | HPMC | PEG 400 | Croscarmellose sodium | 220.5 ± 13.4 | 47.8 ± 2.28 |
| F8 | PVA | PEG 400 | Croscarmellose sodium | 200.7 ± 15.1 | 63.8 ± 3.84 |
| F9 | Pullulan gum | Propylene glycol | Pregelatinized starch | 185.6 ± 14.3 | 66.1 ± 3.24 |
| F10 | Maltodextrin | PEG 400 | Pregelatinized starch | 210.1 ± 14.7 | 54.1 ± 1.92 |
| F11 | HPMC | Propylene glycol | Pregelatinized starch | 240.3 ± 11.4 | 48.3 ± 3.25 |
| F12 | PVA | PEG 400 | Pregelatinized starch | 210.7 ± 15.8 | 58.1 ± 2.82 |
| F13 | Pullulan gum + HPMC (50:50) | Propylene glycol | Croscarmellose sodium | 240.5 ± 18.3 | 34.1 ± 2.31 |
| F14 | Maltodextrin + PVA (50:50) | Propylene glycol | Croscarmellose sodium | 185.3 ± 14.7 | 75.3 ± 4.51 |
The data is represented as Mean ± S.D (n = 3).