. Author manuscript; available in PMC: 2024 Mar 14.

Published in final edited form as: Dev Psychopathol. 2022 Sep 14;34(5):1856–1864. doi: 10.1017/S0954579422000712

Table 2.

Associations between ALDH2/ADH1B status and alcohol-related outcomes

	N	ALDH2		ALDH2 × Age		ADH1B		ADH1B × Age
	N	β (SE)	p-value	β (SE)	p-value	β (SE)	p-value	β (SE)	p-value
Alcohol frequency	786	−.14 (.06)	.0002^*	−.04 (.04)	.29	−.06 (.04)	.11	.01 (.05)	.84
Usual quantity^a	766	−.13 (.04)	.0006^*	−.02 (.03)	.53	−.03 (.04)	.46	.04 (.04)	.28
Max drinks^a	786	−.19 (.04)	<.0001^*	−.10 (.03)	.0047^*	−.05 (.05)	.22	.002 (.04)	.96

Note. All models included genotype, sex, age at assessment (linear and quadratic term), and a genotype × age interaction as fixed effects along with random intercept per individual and slope for age. For both ALDH2 and ADH1B, genotypes of A/A or A/G (i.e., at least one protective allele) are coded as 1. β = standardized coefficient; SE = standard error

denotes variables that were log transformed prior to analysis

denotes p-values below the corrected threshold of 0.005.