Table 4.
Associations between ALDH2 status and other substance-related outcomes*.
| N | ALDH2 | |||
|---|---|---|---|---|
| β/OR | SE | p-value | ||
| Binary measures | ||||
| Ever regular smoker | 320 | 0.98 | 0.32 | 0.95 |
| Marijuana ever | 357 | 0.66 | 0.18 | 0.13 |
| Illegal drug ever | 162 | 0.61 | 0.28 | 0.29 |
| Continuous measures | ||||
| Cigarettes per daya | 698 | −0.05 | 0.06 | 0.41 |
| Marijuana usesa | 704 | 0.06 | 0.08 | 0.28 |
| Illegal drug classes | 284 | 0.02 | 0.09 | 0.86 |
Note. All models included ALDH2 genotype, sex, age at assessment (linear and quadratic term; or year of birth for lifetime measures) as fixed effects along with random intercept per individual and slope for age. ALDH2 genotypes of A/A or A/G (i.e., at least one protective allele) are coded as 1. β = standardized coefficient; OR = odds ratios; SE = standard error
denotes variables that were log transformed prior to analysis
denotes p-values below the corrected threshold of 0.005.