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. Author manuscript; available in PMC: 2024 Mar 14.
Published in final edited form as: Dev Psychopathol. 2022 Sep 14;34(5):1856–1864. doi: 10.1017/S0954579422000712

Table 4.

Associations between ALDH2 status and other substance-related outcomes*.

N ALDH2
β/OR SE p-value
Binary measures
 Ever regular smoker 320 0.98 0.32 0.95
 Marijuana ever 357 0.66 0.18 0.13
 Illegal drug ever 162 0.61 0.28 0.29
Continuous measures
 Cigarettes per daya 698 −0.05 0.06 0.41
 Marijuana usesa 704 0.06 0.08 0.28
 Illegal drug classes 284 0.02 0.09 0.86

Note. All models included ALDH2 genotype, sex, age at assessment (linear and quadratic term; or year of birth for lifetime measures) as fixed effects along with random intercept per individual and slope for age. ALDH2 genotypes of A/A or A/G (i.e., at least one protective allele) are coded as 1. β = standardized coefficient; OR = odds ratios; SE = standard error

a

denotes variables that were log transformed prior to analysis

*

denotes p-values below the corrected threshold of 0.005.