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. 2023 Mar 13;14:1359. doi: 10.1038/s41467-023-36976-1

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — a Four hours after the first (left) and last dose (right) in part B, and b from 0–192 h in patients receiving trotabresib 45 mg/day 4 days on/24 days off. For both figures, colored data points indicate individual patient values for the percentage of baseline CCR1 expression and black lines and error bars indicate mean ± SD. Source data are provided as a source data file. ^aData not shown for one patient with a percentage of baseline CCR1 expression of 1110.93; SD for this time point was 260.36. CCR1 C-C motif chemokine receptor 1, mRNA messenger RNA.