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. 2023 Feb 28;14:1081741. doi: 10.3389/fendo.2023.1081741

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Copyright © 2023 Uglebjerg, Ahmadizar, Aly, Cañadas-Garre, Hill, Naber, Oddsson, Singh, Smyth, Trégouët, Chaker, Ghanbari, Steinthorsdottir, Ahlqvist, Hadjadj, Van Hoek, Kavousi, McKnight, Sijbrands, Stefansson, Simons, Rossing and Ahluwalia

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Flow chart of SNV-eGFRcreatinine meta-analyses in Diabetes. UKBB, UK Biobank; T2D, Type 2 diabetes; DM, diabetes mellitus; T1D, Type 1 diabetes; NDM, without diabetes mellitus; SNV, single nucleotide variant; eGFRcreatinine, Estimated glomerular filtration rate, natural log-transformed; PCs, Principal components of population structure; HbA1C, hemoglobin A1C; SBP, Systolic blood pressure; m1: model 1 (eGFRcreatinine ~ genotype + sex + age + 0-10 PCs); m2: model 2 (m1 + HbA1c + SBP + diabetes duration); * Sample sizes (n) reflect the maximal number of individuals (out of the total number of individuals in Table 1 ) available for rs45551835, model 1. ** See Supplementary Figure 1 for a flow chart of additional analyses. Figure made with LucidChart (lucid.app).