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. 2023 Mar 4;10:367–375. doi: 10.1016/j.toxrep.2023.03.001

Table 1.

Results of the meta-analysis conducted on smoking status and triglyceride (TG) level (mmol/L) data from previous studies. All estimates.


Studies
Effect Estimates Mean Differences in TG levels (mmol/L) (smokers – non-smokers)
Region Fixed Effects [95% CI] I2 (%) Random Effects [95% CI]
US & Canada 23 34 0.08 [0.07, 0.10] 82 0.18 [0.12, 0.23]
Europe 51 73 0.24 [0.24, 0.25] 96 0.21 [0.17, 0.26]
Asia 43 72 0.46 [0.46, 0.47] 100 0.29 [0.20, 0.38]
Latin America 5 5 0.15 [0.00, 0.30] 36 0.17 [− 0.03, 0.36]
Middle East 18 21 0.11 [0.09, 0.13] 97 0.35 [0.23, 0.46]
Indian Subcontinent 23 26 0.76 [0.74, 0.79] 98 0.49 [0.30, 0.68]
Australia 2 4 0.16 [0.03, 0.30] 11 0.18 [0.02, 0.34]
Africa 4 4 0.13 [0.08, 0.17] 87 0.13 [0.00, 0.26]
Study Design
Cross Sectional 143 202 0.13 [0.12, 0.13] 98 0.26 [0.23, 0.30]
Cohort 19 29 0.58 [0.58, 0.58] 99 0.27 [0.19, 0.35]
Case Control 5 6 0.29 [0.25, 0.32] 97 0.40 [0.17, 0.64]
RCT 2 2 NA NA NA
Period of Publication
1970 s 4 5 0.43 [0.38, 0.47] 95 0.30 [0.03, 0.56]
1980 s 24 40 0.25 [0.22, 0.28] 53 0.24 [0.19, 0.30]
1990 s 37 54 0.17 [0.16, 0.18] 82 0.22 [0.18, 0.26]
2000 s 51 72 0.25 [0.24, 0.26] 99 0.23 [0.15, 0.32]
2010 s 43 58 0.08 [0.08, 0.09] 98 0.33 [0.28, 0.38]
2020 s 10 10 0.59 [0.58, 0.59] 100 0.35 [0.24, 0.47]
Smoking Definitiona
None/Other 128 163 0.16 [0.16, 0.17] 98 0.25 [0.21, 0.28]
> 10 CPD 11 12 0.37 [0.31, 0.43] 65 0.34 [0.22, 0.46]
> 15 CPD 9 11 0.41 [0.35, 0.48] 97 0.24 [− 0.19, 0.66]
> 20 CPD 40 53 0.60 [0.60, 0.61] 93 0.33 [0.26, 0.40]
Sexa
Males 82 105 0.30 [0.29, 0.30] 98 0.31 [0.24, 0.37]
Females 35 48 0.05 [0.05, 0.06] 86 0.16 [0.12, 0.19]
Combined 70 86 0.52 [0.52, 0.52] 99 0.29 [0.22, 0.35]
Total 169 239 0.41 [0.41, 0.42] 99 0.27 [0.23, 0.32]
a

The sum of studies does not add to 169, as some studies provided multiple stratum-specific estimates.