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. 2023 Mar 4;10:367–375. doi: 10.1016/j.toxrep.2023.03.001

Table 2.

Results from the meta-analysis of smoking and triglyceride (TG) level (mmol/L) data from previous studies. Estimates for smokers smoking ≥ 15 cigarettes per day.


Studies
Effect Estimates
Mean Differences in TG levels (mmol/L) (smokers – non-smokers)
Region Fixed Effects [95% CI] I2 (%) Random Effects [95% CI]
USA & Canada 11 14 0.16 [0.09, 0.22] 42 0.17 [0.07, 0.27]
Europe 14 21 0.33 [0.31, 0.36] 89 0.22 [0.11, 0.33]
Asia 16 21 0.61 [0.61, 0.61] 86 0.41 [0.30, 0.51]
Middle East 2 3 0.82 [0.73, 0.91] 99 0.64 [− 0.28, 1.56]
Indian Subcontinent 4 4 0.68 [0.56, 0.79] 95 0.66 [0.16, 1.16]
Africa 1 1 NA NA NA
Study Design
Cross Sectional 42 55 0.38 [0.35, 0.40] 92 0.31 [0.21, 0.40]
Cohort 6 9 0.61 [0.61, 0.61] 95 0.42 [0.26, 0.58]
Period of Publication
1970 s 3 3 0.53 [0.48, 0.58] 92 0.35 [0.05, 0.64]
1980 s 15 23 0.19 [0.13, 0.25] 35 0.19 [0.10, 0.27]
1990 s 14 19 0.28 [0.24, 0.31] 72 0.28 [0.21, 0.36]
2000 s 9 11 0.19 [0.13, 0.25] 84 0.20 [0.04, 0.36]
2010 s 6 7 0.82 [ 0.76, 0.88] 96 0.85 [0.52, 118]
2020 s 1 1 NA NA NA
Sexa
Males 27 32 0.38 [0.34, 0.41] 93 0.34 [0.19, 0.48]
Females 10 12 0.18 [0.14, 0.23] 88 0.15 [0.06, 0.24]
Combined 17 20 0.61 [0.61, 0.61] 68 0.43 [0.34, 0.51]
Total 48 64 0.60 [0.60, 0.61] 95 0.32 [0.25, 0.40]
a

The sum of studies does not add to 48, as some studies provided multiple stratum-specific estimates.